إِن تَحْرِصْ عَلَىٰ هُدَىٰهُمْ فَإِنَّ ٱللَّهَ لَا يَهْدِى مَن يُضِلُّ ۖ وَمَا لَهُم مِّن نَّٰصِرِينَ
In tahris 'alaa hudaahum fa innal laaha laa yahdee mai yudillu wa maa lahum min naasireen
[Even] if you should strive for their guidance, [O Muhammad], indeed, Allah does not guide those He sends astray, and they will have no helpers.

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Tafsir

73%48%54%Al-JalalaynIbn AbbasIbn Kathir
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If you O Muhammad (s) are eager for them to be guided when God has already made them go astray you will not be able to achieve this For God does not guide read passive lā yuhdā ? or active lā yahdī he whom He has already sent astray he whom He desires to send astray and they will have no helpers no protectors from God’s chastisement.

Related Hadiths

Jami` at-Tirmidhi #3337Narrated Abu Umamah:Sahih
that the Messenger of Allah (ﷺ) said: "No people go astray after having been guided, but they resort to arguing." Then the Messenger of Allah (ﷺ) recited this Ayah: '...They quoted not the above example except for argument. Nay! But they are quarrelsome people... (43:58)'
Sunan Ibn Majah #4127It was narrated that Abu Umamah said:Hasan
"The Messenger of Allah (ﷺ) said: 'No people go astray after having followed right guidance, but those who indulge in disputes.' Then he recited the Verse: "Nay! But they are a quarrelsome people.'"
Sunan an-Nasa'i #2592It was narrated from Ibn Al-Firasi that Al-Firasi said to the Messenger of Allah:Da'if
"Shall I ask people (for help), O Messenger of Allah?" He said: "No, but if you have no alternative but to ask, then ask the righteous."
Sunan Abu Dawud #3579Narrated Anas ibn Malik:Sahih
The Prophet (ﷺ) said: If anyone desires the office of Judge and seeks help for it, he will be left to his own devices; if anyone does not desire it, nor does he seek help for it, Allah will send down an angel who will direct him aright. Waki' said: (This tradition has also been transmitted) by Isra'il, from 'Abd al-A'la, from Bilal bin Abi Musa, from Anas, from the Prophet (ﷺ). Abu 'Awanah said: from 'Abd al-A'la, from Bilal bin Mirdas al-Fazari, from Khaithamah al-Basri from Anas.
Sunan Abu Dawud #4819Narrated Umar ibn al-Khattab:Sahih
The Prophet (ﷺ) said: the same occasion: Help the oppressed (sorrowful) and guide those who have lost their way.

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About Quran 16:37