فَلَا تُطِعِ ٱلْكَٰفِرِينَ وَجَٰهِدْهُم بِهِۦ جِهَادًۭا كَبِيرًۭا
Falaa tuti'il kaafireena wa jaahidhum bihee jihaadan kabeeraa
So do not obey the disbelievers, and strive against them with the Qur'an a great striving.

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Tafsir

77%32%33%Al-JalalaynIbn AbbasIbn Kathir
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So do not obey the disbelievers in their desires but struggle against them therewith that is through adherence to the Qur’ān with a great endeavour.

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About Quran 25:52