وَرَبُّكَ ٱلْغَنِىُّ ذُو ٱلرَّحْمَةِ ۚ إِن يَشَأْ يُذْهِبْكُمْ وَيَسْتَخْلِفْ مِنۢ بَعْدِكُم مَّا يَشَآءُ كَمَآ أَنشَأَكُم مِّن ذُرِّيَّةِ قَوْمٍ ءَاخَرِينَ
Wa Rabbukal ghaniyyu zur rahmah; iny yashaaa yuz hibkum wa yastakhlif mim ba'dikum wa yastakhlif mim ba'dikum maa yashaaa'u kamaaa ansha akum min zurriyyati qawmin aakhareen
And your Lord is the Free of need, the possessor of mercy. If He wills, he can do away with you and give succession after you to whomever He wills, just as He produced you from the descendants of another people.

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Tafsir

78%50%53%Al-JalalaynIbn AbbasIbn Kathir
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Your Lord is Independent of His creatures and their worship the Lord of Mercy. If He will He can remove you O people of Mecca by destroying you and leave whom He will of creatures to succeed after you just as He produced you from the seed of another folk whom He removed; but He has spared you as a mercy to you.

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About Quran 6:133