أُو۟لَٰٓئِكَ ٱلَّذِينَ حَبِطَتْ أَعْمَٰلُهُمْ فِى ٱلدُّنْيَا وَٱلْءَاخِرَةِ وَمَا لَهُم مِّن نَّٰصِرِينَ
Ulaaa'ikal lazeena habitat a'maaluhum fid dunyaa wal Aaakhirati wa maa lahum min naasireen
They are the ones whose deeds have become worthless in this world and the Hereafter, and for them there will be no helpers.

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Tafsir

81%44%41%Al-JalalaynIbn AbbasIbn Kathir
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Those are the ones whose works what good they did in the way of charity and kindness to kin have failed whose works are invalid in this world and the Hereafter and so they have nothing to reckon with since these works are of no consequence; they have no helpers no protectors from the chastisement.

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About Quran 3:22